Odontogenic tumors are heterogeneous group of lesions with diverse histopathological and clinical features. Ameloblastic fibro-dentinoma. The ameloblastic fibro-odontoma (AFO) is a rare mixed odontogenic tumor. .. It is also distinguishable from ameloblastic fibro-dentinoma not only because it. Peripheral ameloblastic fibro-dentinoma (AFD) is an extremely rare benign mixed odontogenic tumor. From a review of the English-language literature, to the.

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Report of two cases.

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A proper clinical, radiological and histological corelation should be established before considering a lesion as a benign or a malignant variant, and the treatment should be planned accordingly. Common signs and symptoms of AFO are asymptomatic swelling, delayed tooth eruption in the affected region and a well-defined mixed radiological appearance that is similar to other odontogenic neoplastic formations, such as immature complex odontoma, calcifying epithelial odontogenic tumour and adenomatoid odontogenic tumour.

The treatment of AFO is associated with conservative ameloblatic approach. Considering the clinical and radiological picture the possible differential diagnosis was calcifying epithelial odontogenic tumour CEOTadenomatoid odontogenic tumour AOT and ameloblastic fibro-odontoma.

After the lesion had been locally debrided and irrigated with 0. Immediately after the eruption, it was positioned more palatally than the adjacent incisors.

The radiograph showed expansion and thinning of the cortex. Kannan Venugopal was responsible for writing the article.

Odontogenic tumors are heterogeneous group of lesions with diverse histopathological and clinical features.

A one-year postoperative follow-up revealed no evidence of recurrence, but only a mild gingival inflammation Figure 3. Isotype immunoglobulins Abcam were used to replace primary antibodies as negative control. The diagnosed and treated cases should be kept under regular follow-up in order to rule out any evidence of recurrence and malignant transformation. Int J Surg Case Rep. Considerably more information on the AFD has to be amelloblastic in order to better understand the lesion, its biological behavior, risk of malignant transformation and relationship to the other AF-related lesion.


The substance of the radiolucent area showed few flecks of radioopacity. Some other reports demonstrated that a conservative enucleation is enough.

Ameloblastic fibro-odontoma

Based on the existing literature, amelogenin secreted by the odontogenic epithelium may contribute to the red appearance of the lesion.

A pre-operative differential diagnosis of calcifying epithelial odontogenic tumor, mixed odontogenic tumor, calcifying odontogenic cyst and fibrosseous lesion was given. To receive news and publication updates for Case Reports in Dentistry, enter your email address in the box below.

Odontogenic Tumors and Allied Lesions.

While in some other cases, hyalinised area containing entrapped cells has been considered as an abortive dentine or dentinoid tissue because of its proximity to the odontogenic epithelial. Open in a separate window. Pathology and genetics of head and neck tumours. Discussion Ameloblastic fibro-odontoma AFO is an uncommon mixed odontogenic tumour. On higher-power magnification, the odontogenic epithelial component consisted of multiple follicles and islands of tall columnar to cuboidal ameloblast-like cells with reversed nuclear polarity.

Support Center Support Center. Hematoxylin and eosin staining for the gingival lesion. Ameloblastic fibroma and related lesions: The recurrence rate of intraosseous AFO is uncommon: Contemp Clin Dent ; 3: Amoxicillin and acetaminophen were prescribed for the patient.


Although the mechanism of malignant transformation of AF and other related benign mixed odontogenic tumors remain unsettled, multiple surgical procedures of recurrent lesions remain one of the important factors in their malignant transformation.

The peripheral types of mixed odontogenic tumors are much rarer than their intraosseous counterparts [ 1 — 6 ]. Indexed in Web of Science. On gross examination the specimen consisted of a hard tissue mass with a soft tissue attachment. National Center for Biotechnology InformationU.

Clinicians when dealing with radiopaque mass in posterior maxilla of children should keep the possibility of rare mixed odontogenic tumour in mind. However, in view of the absence of mitotic demtinoma and, secondly, in correlation to the clinical and radiographic presentation of the lesion, a diagnosis of aggressive atypical AFD was made.

J Oral Pathol Med.

Aggressive atypical ameloblastic fibrodentinoma: Report of a case

Ameloblastic fibrodentinoma of mandible. There may be two reasons for the high vascularization of this lesion. Recurrence of an ameloblastic fibro-odontoma in a 9-year-old boy. The mesenchymal component was primitive connective tissue resembling the dental papilla of the tooth germ. A study of 1, cases from Northern California and comparison to studies from other parts of the dentinomaa.